Article
Tachykinin 1 (TAC1) gene SNPs and haplotypes with autism: a case-control study.
Brain & development - 1 Sept 2007
Marui Tetsuya, Funatogawa Ikuko, Koishi Shinko, Yamamoto Kenji, Matsumoto Hideo, Hashimoto Ohiko, Nanba Eiji, Nishida Hisami, Sugiyama Toshiro, Kasai Kiyoto, Watanabe Keiichiro, Kano Yukiko, Kato Nobumasa, Sasaki Tsukasa
Abstract excerpt
Autism (MIM 209850) is a severe neurodevelopmental disorder characterized by disturbances in social interaction and communication, by repetitive body movements and restricted interests, and by atypical language development. Several twin and family studies have shown strong evidence for genetic factors in the etiology of autism. Glutamate is a major excitatory neurotransmitter in the human brain. Glutamate systems...
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