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Article

Mutation of the INI1 gene in composite rhabdoid tumor of the endometrium.

Human pathology - 1 Jun 2007

Donner Ludvik R, Wainwright Luanne M, Zhang Fan, Biegel Jaclyn A

Abstract excerpt

Composite rhabdoid tumors are typically adult tumors that contain a component of rhabdoid cells, which are characteristic of the aggressive childhood malignant rhabdoid tumor. Pediatric rhabdoid tumors are characterized by the inactivation of the hSNF5/INI1/SMARCB1 gene, with subsequent loss of expression of the protein. In contrast, only a single composite rhabdoid tumor has demonstrated involvement of the INI1...

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Share to Chromosomal Proteins, Non-Histone
Share to DNA-Binding Proteins
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Polymerase Chain Reaction

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Source

Open in PubMed Open full text

Identifiers

PMID: 17376508
DOI: 10.1016/j.humpath.2006.12.003
PMCID: PMC1963314

Genes

SMARCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Mutation of the INI1 gene in composite rhabdoid tumor of the endometrium.PMID 17376508Read ↗

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Uterine neoplasms composed of rhabdoid cells do not exhibit loss of INI1 immunoreactivity and are not related to childhood malignant rhabdoid tumor.Semantic proximity Read ↗

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The expanding family of SMARCB1(INI1)-deficient neoplasia: implications of phenotypic, biological, and molecular heterogeneity.Semantic proximity Read ↗

Cyclin D1 is overexpressed in atypical teratoid/rhabdoid tumor with hSNF5/INI1 gene inactivation.Semantic proximity Read ↗

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