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Article

What's new in karyotyping? The move towards array comparative genomic hybridisation (CGH).

European journal of pediatrics - 1 Jul 2007

de Ravel Thomy J L, Devriendt Koen, Fryns Jean-Pierre, Vermeesch Joris R

Abstract excerpt

Molecular karyotyping by array comparative genomic hybridisation (array CGH) has doubled the detection rate of pathogenic chromosomal imbalances in patients. This has been possible by increasing the resolution level from the 5 Mb obtained using the conventional karyotype to as low as 100 kb by array technology. Moreover, the technology revealed that over 12% of the human genome includes sub-microscopic benign...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17372759
DOI: 10.1007/s00431-007-0463-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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