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Human sperm bound to the zona pellucida have normal nuclear chromatin as assessed by acridine orange fluorescence

16 Mar 2007

Abstract excerpt

BACKGROUND: The aim of this study was to determine if only sperm with double stranded DNA could bind to the human zona pellucida (ZP). METHODS: Sperm samples from 124 infertile men with a range of semen abnormalities were studied. Oocytes that had failed to fertilize in IVF or ICSI were used for the sperm-ZP binding test. A group of four oocytes were incubated for 2 h with 2 x 10(6)/ml motile sperm selected by...

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PMID: 17369294
DOI: 10.1093/humrep/dem044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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