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Article

High frequency of defective sperm-zona pellucida interaction in oligozoospermic infertile men

1 Feb 2004

Abstract excerpt

BACKGROUND: The ability of sperm to interact with the zona pellucida (ZP) plays a critical role during the process of human fertilization. The aim of this study is to determine frequency of defective sperm-ZP interaction in oligozoospermic infertile men. METHODS: Sperm-ZP binding assays and the ZP-induced acrosome reaction (AR) were performed in 72 infertile men with a sperm concentration <20 x 10(6)/ml. Oocytes...

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PMID: 14747159
DOI: 10.1093/humrep/deh067

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