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Article

A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD.

Neurobiology of aging - 1 Aug 2008

Belbin O, Dunn J L, Chappell S, Ritchie A E, Ling Y, Morgan L, Pritchard A, Warden D R, Lendon C L, Lehmann D J, Mann D M A, Smith A D, Kalsheker N, Morgan K

Abstract excerpt

There is biochemical and animal model evidence supporting a pathological role of the ACT gene in AD. However, direct genetic evidence remains controversial and has been mostly limited to individual single nucleotide polymorphism (SNP) analysis. To resolve this apparent conflict we have used a hig...

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PMID: 17368652
DOI: 10.1016/j.neurobiolaging.2007.02.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17368652-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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