Article
Molecular mechanisms of copper homeostasis.
Frontiers in bioscience (Landmark edition) - 1 Jun 2009
Lalioti Vasiliki, Muruais Gemma, Tsuchiya Yo, Pulido Diego, Sandoval Ignacio V
Abstract excerpt
The transition metal copper (Cu) is an essential trace element for all biota. Its redox properties bestow Cu with capabilities that are simultaneously essential and potentially damaging to the cell. Free Cu is virtually absent in the cell. The descriptions of the structural and functional organization of the metallothioneins, Cu-chaperones and P-type ATPases as well as of the mechanisms that regulate their...
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