Article
Sensitive method for identification of minor hepatitis B mutant viruses.
Virology - 1 Mar 1992
Grötzinger T, Will H
Abstract excerpt
There is increasing evidence for selection of hepatitis B virus (HBV) mutants during the natural course of infection, after immunization, and during interferon therapy. These mutants can prolong viral persistence, escape immune-mediated elimination, and influence the clinical sequelae of infectio...
Topics
- Base Sequence
- Cloning, Molecular
- DNA, Viral
- Hepatitis B virus
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
