Article
Effects of polymorphisms of chemokine receptors on neurodevelopment and the onset of encephalopathy in children with perinatal HIV-1 infection.
Applied neuropsychology - 1 Jan 2006
Llorente Antolin, Brouwers Pim, Thompson Bruce, Cheng Irene, Macmillan Carol, Larussa Phillip, Mofenson Lynne, Blasini Ileana, Chase Cynthia
Abstract excerpt
This study examined the effects of chemokine receptor polymorphisms on neurodevelopment and the onset of encephalopathy in children with perinatal HIV-1 infection. Infected children (N = 121) between the ages of I and 72 months were categorized into dichotomous groups (heterozygous or homozygous mutant vs. homozygous wild type) for each chemokine receptor 2 (CCR2) and chemokine receptor 5 (CCR5) allele....
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