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Article

Small RNA-mediated chromatin silencing directed to the 3' region of the Arabidopsis gene encoding the developmental regulator, FLC.

Proceedings of the National Academy of Sciences of the United States of America - 27 Feb 2007

Swiezewski Szymon, Crevillen Pedro, Liu Fuquan, Ecker Joseph R, Jerzmanowski Andrzej, Dean Caroline

Abstract excerpt

Small RNA-mediated chromatin silencing is well characterized for repeated sequences and transposons, but its role in regulating single-copy endogenous genes is unclear. We have identified two small RNAs (30 and 24 nucleotides) corresponding to the reverse strand 3' to the canonical poly(A) site of FLOWERING LOCUS C (FLC), an Arabidopsis gene encoding a repressor of flowering. Genome searches suggest that these...

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Identifiers

PMID: 17360694
DOI: 10.1073/pnas.0611459104
PMCID: PMC1805594

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