Article
A polyphosphate kinase 1 (ppk1) mutant of Pseudomonas aeruginosa exhibits multiple ultrastructural and functional defects.
Proceedings of the National Academy of Sciences of the United States of America - 27 Feb 2007
Fraley Cresson D, Rashid M Harunur, Lee Sam S K, Gottschalk Rebecca, Harrison Janine, Wood Pauline J, Brown Michael R W, Kornberg Arthur
Abstract excerpt
Pseudomonas aeruginosa, of medical, environmental, and industrial importance, depends on inorganic polyphosphate (poly P) for a wide range of functions, especially survival. Mutants of PAO1 lacking poly P kinase 1, PPK1, the enzyme responsible for most poly P synthesis in Escherichia coli and other bacteria, are defective in motility, quorum sensing, biofilm formation, and virulence. We describe here multiple...
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