Article
Inherited susceptibility to acute pyelonephritis: a family study of urinary tract infection.
The Journal of infectious diseases - 15 Apr 2007
Lundstedt Ann-Charlotte, Leijonhufvud Irene, Ragnarsdottir Bryndis, Karpman Diana, Andersson Björn, Svanborg Catharina
Abstract excerpt
BACKGROUND: Urinary tract infections (UTIs) are important causes of morbidity and death. The present study investigated whether genetic factors influence susceptibility to acute pyelonephritis (APN). CXCR1 expression was investigated as a factor predisposing to APN, because low CXCR1 expression has been associated with disease susceptibility in mice and disease-prone children. METHODS: The families of APN-prone...
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