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Article

A gene duplication led to specialized gamma-aminobutyrate and beta-alanine aminotransferase in yeast.

The FEBS journal - 1 Apr 2007

Andersen Gorm, Andersen Birgit, Dobritzsch Doreen, Schnackerz Klaus D, Piskur Jure

Abstract excerpt

In humans, beta-alanine (BAL) and the neurotransmitter gamma-aminobutyrate (GABA) are transaminated by a single aminotransferase enzyme. Apparently, yeast originally also had a single enzyme, but the corresponding gene was duplicated in the Saccharomyces kluyveri lineage. SkUGA1 encodes a homologue of Saccharomyces cerevisiae GABA aminotransferase, and SkPYD4 encodes an enzyme involved in both BAL and GABA...

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Source

Identifiers

PMID: 17355287
DOI: 10.1111/j.1742-4658.2007.05729.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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