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Article

Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy.

Circulation research - 30 Mar 2007

Osio Adriana, Tan Lily, Chen Suet N, Lombardi Raffaella, Nagueh Sherif F, Shete Sanjay, Roberts Robert, Willerson James T, Marian Ali J

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is a genetic disorder caused by mutations in sarcomeric proteins (excluding phenocopy). The causal genes in approximately one-third of the cases remain unknown. We identified a family comprised of 6 clinically affected members. The phenotype was characterized by early onset of symptoms, pronounced cardiac hypertrophy, and cardiac arrhythmias. We excluded MYH7, MYBPC3, TNNT2, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17347475
DOI: 10.1161/01.RES.0000263008.66799.aa
PMCID: PMC2775141

Genes

MYOZ2
ACTC1
MYBPC3
MYH7
TNNT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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