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Clinical presentation of Crohn's disease. association between familial disease, smoking, disease phenotype, extraintestinal manifestations and need for surgery.

Hepato-gastroenterology - 1 Jan 2000

Lakatos Peter Laszlo, Szalay Ferenc, Tulassay Zsolt, Molnar Tamas, Kovacs Agota, Gasztonyi Beata, Papp Janos, Lakatos Laszlo

Abstract excerpt

BACKGROUND/AIMS: Recent molecular data suggest that genetic factors may underlie the disease heterogeneity observed in Crohn's disease (CD). It was also suggested that familial inflammatory bowel disease (IBD) is a homogenous subgroup, phenotypically different from sporadic disease. Our aim was to determine the clinical presentation in a large CD population. METHODOLOGY: 564 CD patients (m/f: 278/286, age: 37.4...

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PMID: 15966211

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