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Article

Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2007

Rodriguez-Pinilla Socorro M, Sarrio David, Moreno-Bueno Gema, Rodriguez-Gil Yolanda, Martinez Miguel A, Hernandez Lucia, Hardisson David, Reis-Filho Jorge S, Palacios Jose

Abstract excerpt

Tumours arising in BRCA1 mutation carriers and sporadic basal-like breast carcinomas have similar phenotypic, immunohistochemical and clinical characteristics. SOX2 is an embryonic transcription factor located at chromosome 3q, a region frequently gained in sporadic basal-like and BRCA1 germline mutated tumours. The aim of the study was to establish whether sox2 expression was related to basal-like sporadic...

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Source

Identifiers

PMID: 17334350
DOI: 10.1038/modpathol.3800760

Genes

EGFR
BRCA1
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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