Article
Sleep-related epilepsy in the A/J mouse.
Sleep - 1 Feb 2007
Strohl Kingman P, Gallaugher Laura, Lynn Audrey, Friedman Lee, Hill Annie, Singer Jonathan B, Lander Eric S, Nadeau Joseph
Abstract excerpt
RATIONALE: Evident seizures during sleep are common in clinical practice but are uncommonly considered in animal models of epilepsy. A previous observation of spontaneous spike-and-wave activity during sleep in several A/J mice (A/J JAX) from Jackson Laboratory (Bar Harbor, ME) prompted this description of the inheritance of epileptic activity. METHODS: Mice from A/J, C57BI/6J (B6), and chromosomal substitutions...
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