Article
The Pro12Ala polymorphism of the PPAR gamma 2 gene influences sex hormone-binding globulin level and its relationship to the development of the metabolic syndrome in young Finnish men.
Endocrine - 1 Oct 2006
Mousavinasab Firoozeh, Tähtinen Tuula, Jokelainen Jari, Koskela Pentti, Vanhala Mauno, Oikarinen Jorma, Laakso Markku, Keinänen-Kiukaanniemi Sirkka
Abstract excerpt
Association of low sex hormone-binding globulin (SHBG) level with the risk of the metabolic syndrome (MetS) in men has previously been reported. A proline to alanine substitution in codon 12 of the peroxisome proliferator activated receptor gamma 2 (PPARgamma2) gene has been shown to be related to high insulin sensitivity. The relationship of SHBG levels with the Pro12Ala polymorphism of PPARgamma2 in men has not...
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