Article
DRB genotyping in cynomolgus monkeys from China using polymerase chain reaction -sequence-specific primers.
Human immunology - 1 Feb 2007
Wei Huafeng, Wang Hao, Hou Sheng, Hu Shuiqing, Fan Kexing, Fan Xiaoqiang, Zhu Tongyu, Guo Yajun
Abstract excerpt
Cynomolgus macaques are relevant models for human diseases and transplantation. In each case, a complete understanding of these models requires knowledge of the macaque major histocompatibility complex (MHC). Because of high polymorphism and multiple genes per haplotype, it has been difficult to develop a rapid typing method for cynomolgus monkey MHC class II. We developed a simple and rapid polymerase chain...
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