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Identification of DRB alleles in rhesus monkeys using polymerase chain reaction-sequence-specific primers (PCR-SSP) amplification.

Tissue antigens - 1 Sept 1999

Lobashevsky A, Smith J P, Kasten-Jolly J, Horton H, Knapp L, Bontrop R E, Watkins D, Thomas J

Abstract excerpt

Major histocompatibility complex (MHC) class In molecules play a vital role in the regulation of T-cell functions in the mammalian immune system. Two key features characterize the polymorphism of MHC haplotypes in humans and non-human primates: the existence of a large number of alleles, and the high degree of genetic diversity between those alleles. Rhesus monkeys and Chimpanzees have been extensively used as...

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PMID: 10519362
DOI: 10.1034/j.1399-0039.1999.540306.x

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