Article
Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets.
Molecular cell - 23 Feb 2007
Krol Jacek, Fiszer Agnieszka, Mykowska Agnieszka, Sobczak Krzysztof, de Mezer Mateusz, Krzyzosiak Wlodzimierz J
Abstract excerpt
Ribonuclease Dicer functions in cells to excise microRNAs from their precursors and process long double-stranded RNAs into short interfering RNAs. We show that transcripts containing long hairpin structures composed of CNG repeats are another class of Dicer targets. The cellular levels of transcr...
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