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Article

Panhypopituitarism: genetic versus acquired etiological factors.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Jan 2007

Coya R, Vela A, Pérez de Nanclares G, Rica I, Castaño L, Busturia M A, Martul P

Abstract excerpt

OBJECTIVE: Mutations in the genes encoding pituitary transcription factors (mainly PROP1, POUF1 and HESX1) are responsible for familial combined pituitary hormone deficiency (CPHD) and septo-optic dysplasia (SOD) while only a low percentage of mutations are the cause of sporadic forms. Indeed, it has been suggested that environmental rather than genetic factors could be important in the pathogenesis of CPHD....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17315526
DOI: 10.1515/jpem.2007.20.1.27

Genes

HESX1
PROP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Panhypopituitarism: genetic versus acquired etiological factors.PMID 17315526Read ↗

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