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Article

Reduction of HIV-1 RNA Levels with Therapy to Suppress Herpes Simplex Virus

21 Feb 2007

Abstract excerpt

BACKGROUND: Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS: We conducted a randomized, double-blind, placebo-controlled trial of HSV suppressive therapy with valacyclovir (at a dose of 500 mg twice daily) in Burkina Faso among women who were...

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Share to Cervical Cancer and HPV Research
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PMID: 17314338
DOI: 10.1056/nejmoa062607

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