Article
A differential ligand-mediated response of green fluorescent protein-tagged androgen receptor in living prostate cancer and non-prostate cancer cell lines.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Jun 2007
Nakauchi Hiroo, Matsuda Ken-ichi, Ochiai Ikuo, Kawauchi Akihiro, Mizutani Yoichi, Miki Tsuneharu, Kawata Mitsuhiro
Abstract excerpt
Androgen has been shown to promote the proliferation of prostate cancer through the action of the androgen receptor (AR). Mutation (T877A) of the AR gene found in an androgen-sensitive prostate cancer cell line, LNCaP, has been postulated to be involved in hypersensitivity and loss of specificity...
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