Article
Urea sensitization caused by separation of Helicobacter pylori RNA polymerase beta and beta' subunits.
Helicobacter - 1 Apr 2007
Dailidiene Daiva, Tan Shumin, Ogura Keiji, Zhang Maojun, Lee Amy H, Severinov Konstantin, Berg Douglas E
Abstract excerpt
BACKGROUND: The beta and beta' subunits of RNA polymerase are fused in all Helicobacters, but separate in most other taxa. Prior studies had shown that this fusion is not essential for viability in culture or in vivo, but had not tested it for potentially important quantitative effects on phenotype. METHODS: The effect of separating rpoB and rpoC sequences on Helicobacter pylori growth was tested in culture and...
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