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Article

Stable expression of Gal/GalNAc lectin of <i>Entamoeba histolytica</i> in transgenic chloroplasts and immunogenicity in mice towards vaccine development for amoebiasis

25 Jan 2007

Abstract excerpt

Chloroplast genetic engineering offers several advantages, including high levels of transgene expression, transgene containment via maternal inheritance and multigene engineering in a single transformation event. Entamoeba histolytica infects 50 million people, causing about 100,000 deaths annually, but there is no approved vaccine against this pathogen. LecA, a potential target for blocking amoebiasis, was...

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PMID: 17309678
DOI: 10.1111/j.1467-7652.2006.00234.x

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