Article
The p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors.
Molecular and cellular biology - 1 Apr 2007
Saveanu Cosmin, Rousselle Jean-Claude, Lenormand Pascal, Namane Abdelkader, Jacquier Alain, Fromont-Racine Micheline
Abstract excerpt
Ribosome biogenesis is driven by a large number of preribosomal factors that associate with and dissociate from the preribosomal particles along the maturation pathway. We have previously shown that budding yeast Mak11, whose homologues in other eukaryotes were described as modulating a p21-activated protein kinase function, accumulates in Rlp24-associated pre-60S complexes when their maturation is impeded in...
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