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Article

Hyperhomocysteinaemia and human reproduction.

Clinical chemistry and laboratory medicine - 1 Aug 2001

Nelen W L

Abstract excerpt

Mild hyperhomocysteinaemia has been identified as a risk factor for arterial disease and venous thrombosis. In 1991, elevated homocysteine concentrations were also suggested to be associated with neural tube defects (NTD). Since then this relationship has been reported frequently, as well as the relationship between NTD and the 677 C-->T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene. Meanwhile,...

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Source

Identifiers

PMID: 11592447
DOI: 10.1515/CCLM.2001.126

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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