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Article

The haptoglobin 2-2 genotype is associated with a reduced incidence of Plasmodium falciparum malaria in children on the coast of Kenya.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Mar 2007

Atkinson Sarah H, Mwangi Tabitha W, Uyoga Sophie M, Ogada Edna, Macharia Alex W, Marsh Kevin, Prentice Andrew M, Williams Thomas N

Abstract excerpt

BACKGROUND: Haptoglobin (Hp) genotype determines the efficiency of hemoglobin clearance after malaria-induced hemolysis and alters antioxidant and immune functions. The Hp2 allele is thought to have spread under strong selection pressure, but it is unclear whether this is due to protection from m...

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PMID: 17304451
DOI: 10.1086/511868
PMCID: PMC2659731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17304451-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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