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Article

Structural determinants of Cys2His2 zinc fingers.

FEBS letters - 13 Jan 1992

Mortishire-Smith R J, Lee M S, Bolinger L, Wright P E

Abstract excerpt

Two mutants of the zinc finger peptide Xfin-31 (Ac-YKCGLCERSFVEKSALSRHQRVHKN-CONH2) containing alterations to the conserved hydrophobic core have been constructed and their zinc-bound structures investigated by 1H NMR techniques. In the first (Xfin-31B) a double mutation R8F/F10G places the conserved core aromatic residue at position 8 rather than position 10. In the second (Xfin-31C), Phe-10 is replaced by Leu....

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Identifiers

PMID: 1730285
DOI: 10.1016/0014-5793(92)80392-t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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