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Article

Instant hepatic differentiation of human embryonic stem cells using activin A and a deleted variant of HGF.

Cell transplantation - 1 Jan 2006

Chen Yong, Soto-Gutierrez Alejandro, Navarro-Alvarez Nalu, Rivas-Carrillo Jorge David, Yamatsuji Tomoki, Shirakawa Yasuhiro, Tanaka Noriaki, Basma Hesham, Fox Ira J, Kobayashi Naoya

Abstract excerpt

Human embryonic stem (hES) cells have the ability to differentiate into a variety of different cell lineages and potentially provide a source of differentiated cells for many therapeutic uses. Here we investigated an efficient method of hepatic differentiation from hES cells. A human ES cell line, KhES-1, was used and maintained by a nonfeeder method. KhES-1 cells were cultured for 5 days in the presence of human...

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Identifiers

PMID: 17299990
DOI: 10.3727/000000006783981305

Genes

AFP
FOXA2
HGF
SOX17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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