Article
Association of lipoprotein lipase (LPL) single nucleotide polymorphisms with type 2 diabetes mellitus.
Experimental & molecular medicine - 31 Oct 2008
Cho Yoon Shin, Go Min Jin, Han Hye Ree, Cha Seung Hun, Kim Hung Tae, Min Haesook, Shin Hyoung Doo, Park Chan, Han Bok Ghee, Cho Nam Han, Shin Chol, Kimm Kuchan, Oh Bermseok
Abstract excerpt
The etiology and pathogenesis of type 2 diabetes mellitus (T2DM) are not completely understood although it is often associated with other conditions such as obesity, hypertension, and dyslipidemia. Lipoprotein lipase (LPL) is a key enzyme in human lipid metabolism that facilitates the removal of triglyceride-rich lipoproteins from the bloodstream. LPL hydrolyzes the core of triglyceride-rich lipoproteins...
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