Article
A putative scenario of how de novo protein-coding genes originate in the Saccharomyces cerevisiae lineage.
BMC genomics - 5 Sept 2024
Yada Tetsushi, Taniguchi Takeaki
Abstract excerpt
BACKGROUND: Novel protein-coding genes were considered to be born by re-organization of pre-existing genes, such as gene duplication and gene fusion. However, recent progress of genome research revealed that more protein-coding genes than expected were born de novo, that is, gene origination by accumulating mutations in non-genic DNA sequences. Nonetheless, the in-depth process (scenario) for de novo origination...
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