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Non-invasive aneuploidy detection using free fetal DNA and RNA in maternal plasma: recent progress and future possibilities

12 Nov 2010

Abstract excerpt

BACKGROUND: Cell-free fetal DNA (cff DNA) and RNA can be detected in maternal plasma and used for non-invasive prenatal diagnostics. Recent technical advances have led to a drastic change in the clinical applicability and potential uses of free fetal DNA and RNA. This review summarizes the latest clinical developments in non-invasive prenatal diagnosis in the context of the latest technical developments. METHODS:...

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Share to Fetal and Pediatric Neurological Disorders
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PMID: 21076134
DOI: 10.1093/humupd/dmq054

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