RNA degradation in fission yeast mitochondria is stimulated by a member of a new family of proteins that are conserved in lower eukaryotes.

doi:10.1016/j.jmb.2007.01.014

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Article

RNA degradation in fission yeast mitochondria is stimulated by a member of a new family of proteins that are conserved in lower eukaryotes.

Journal of molecular biology - 30 Mar 2007

Wiesenberger Gerlinde, Speer Falk, Haller Günter, Bonnefoy Nathalie, Schleiffer Alexander, Schafer Bernd

Abstract excerpt

We report here on the role of open reading frame (ORF) SPCC1183.04c of Schizosaccharomyces pombe in mitochondrial RNA metabolism. A mutant deleted for this ORF on chromosome III accumulates mitochondrial transcripts with the exception of the cob mRNA. A detailed Northern blot analysis showed that the effect results from a decrease in RNA degradation but not from RNA processing deficiencies. Overexpression of the...

Topics

Amino Acid Sequence
Base Sequence
Conserved Sequence
DNA, Fungal
Genes, Fungal
Genetic Complementation Test
Mitochondria
Molecular Sequence Data
Mutation
Open Reading Frames
Phenotype
RNA
RNA Processing, Post-Transcriptional

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Fungal

RNA, Mitochondrial

Recombinant Proteins

Saccharomyces cerevisiae

Schizosaccharomyces

Source

Open in PubMed

Identifiers

PMID: 17292401
DOI: 10.1016/j.jmb.2007.01.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.