Article
[Study on polymorphisms in metabolic enzyme genes, DNA repair genes and individual susceptibility to hepatocellular carcinoma].
Wei sheng yan jiu = Journal of hygiene research - 1 Nov 2006
Ye Xin-ping, Peng Tao, Li Le-qun
Abstract excerpt
Hepatocellualr carcinoma is one of the most malignancy, and the pathogenesis has not been clarified yet. The individual variation in the capacity of xenobiotic metabolizing and DNA repair was the genetic susceptibility to malignancies. Studies on polymorphisms of metabolic enzymes (CYP, NAT, GST, EH, ALDH) and DNA repair genes (XRCC1,hOGG1,XPD), and susceptibility to hepatocellular carcinoma are reviewed in this...
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