Article
Preliminary investigation of follistatin gene mutations in women with polycystic ovary syndrome.
Molecular human reproduction - 1 Jul 2000
Liao W X, Roy A C, Ng S C
Abstract excerpt
Strong evidence for a link between the follistatin gene and polycystic ovary syndrome (PCOS) has recently been found in a well-designed large-scale study. Follistatin binds to activin and affects its functions, e.g. stimulation of FSH synthesis and secretion. Thus, it may play a role in the functional impairment of the FSH-granulosa cell axis in PCOS. In this study, we screened 64 Chinese patients with PCOS for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.