Article
RhoA, encoding a Rho GTPase, is associated with smoking initiation.
Genes, brain, and behavior - 1 Nov 2007
Chen X, Che Y, Zhang L, Putman A H, Damaj I, Martin B R, Kendler K S, Miles M F
Abstract excerpt
We used microarray analysis of acute nicotine responses in mouse brain to choose rationale candidates for human association studies on tobacco smoking and nicotine dependence (ND). Microarray studies on the time-course of acute response to nicotine in mouse brain identified 95 genes regulated in ventral tegmental area. Among these, 30 genes were part of a gene network, with functions relevant to neural...
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