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A new isoform of human membrane-bound IgE

1 Jan 1992

Abstract excerpt

The epsilon-chain of membrane-bound IgE on the surface of B lymphocytes is known to contain a membrane-anchoring peptide segment that is encoded by two membrane exons, me.1 and me.2. In analyzing pertinent segments in mRNA from human IgE-expressing B cells by using PCR methods and Northern blotting analyses, we have identified three species of mRNA of epsilon-chain with variations in the splicing of the membrane...

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PMID: 1727861
DOI: 10.4049/jimmunol.148.1.129

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