Article
Long-term T-cell reconstitution after hematopoietic stem-cell transplantation in primary T-cell-immunodeficient patients is associated with myeloid chimerism and possibly the primary disease phenotype.
Blood - 15 May 2007
Cavazzana-Calvo Marina, Carlier Frédérique, Le Deist Françoise, Morillon Estelle, Taupin Pierre, Gautier David, Radford-Weiss Isabelle, Caillat-Zucman Sophie, Neven Bénédicte, Blanche Stephane, Cheynier Rémi, Fischer Alain, Hacein-Bey-Abina Salima
Abstract excerpt
We studied T-cell reconstitution in 31 primary T-cell-immunodeficient patients who had undergone hematopoietic stem-cell transplantation (HSCT) over 10 years previously. In 19 patients, there was no evidence of myeloid chimerism because little or no myeloablation had been performed. Given this context, we sought factors associated with good long-term T-cell reconstitution. We found that all patients having...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.