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Article

Structural Characterization of <i>Campylobacter jejuni</i> Lipooligosaccharide Outer Cores Associated with Guillain-Barre and Miller Fisher Syndromes

2 Feb 2007

Abstract excerpt

Molecular mimicry between lipooligosaccharides (LOS) of Campylobacter jejuni and gangliosides in peripheral nerves plays a crucial role in the pathogenesis of C. jejuni-related Guillain-Barré syndrome (GBS). We have analyzed the LOS outer core structures of 26 C. jejuni strains associated with GBS and its variant, Miller Fisher syndrome (MFS), by capillary electrophoresis coupled with electrospray ionization mass...

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PMID: 17261613
DOI: 10.1128/iai.00872-06

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