Article
Interaction(s) between essential fatty acids, eicosanoids, cytokines, growth factors and free radicals: relevance to new therapeutic strategies in rheumatoid arthritis and other collagen vascular diseases.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Dec 1991
Das U N
Abstract excerpt
Eicosanoids, lymphokines, and free radicals are known to participate in the pathogenesis of inflammation. Tumour necrosis factor (TNF), interleukin-1 and 6 (IL-1 and IL-6) and colony stimulating factor -1 (CSF-1) are secreted mainly by activated macrophages, whereas T-cells secrete IL-2, IL-3, IL...
Topics
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Collagen Diseases
- Cytokines
- Disease Susceptibility
- Drug Synergism
- Drug Therapy, Combination
- Eicosanoids
- Fatty Acids, Essential
- Free Radicals
- Genetic Predisposition to Disease
- Growth Substances
- HLA-DR Antigens
- Humans
- Immunologic Factors
- Immunosuppressive Agents
- Inflammation
- Neovascularization, Pathologic