Article
Type 2 diabetes-associated missense polymorphisms KCNJ11 E23K and ABCC8 A1369S influence progression to diabetes and response to interventions in the Diabetes Prevention Program.
Diabetes - 1 Feb 2007
Florez Jose C, Jablonski Kathleen A, Kahn Steven E, Franks Paul W, Dabelea Dana, Hamman Richard F, Knowler William C, Nathan David M, Altshuler David
Abstract excerpt
The common polymorphisms KCNJ11 E23K and ABCC8 A1369S have been consistently associated with type 2 diabetes. We examined whether these variants are also associated with progression from impaired glucose tolerance (IGT) to diabetes and responses to preventive interventions in the Diabetes Prevent...
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