Article
Placental transfer of quetiapine in relation to P-glycoprotein activity.
Journal of psychopharmacology (Oxford, England) - 1 Sept 2007
Rahi Melissa, Heikkinen Tuija, Härtter Sebastian, Hakkola Jukka, Hakala Kristo, Wallerman Ola, Wadelius Mia, Wadelius Claes, Laine Kari
Abstract excerpt
Atypical antipsychotic drugs are well tolerated and thus often preferred in women of fertile age; yet the information on their placental transfer and use during the prenatal period is limited. The aim of this study was to study the placental transfer of quetiapine, a widely used atypical antipsychotic, with special reference to the role of the placental transporter protein, P-glycoprotein (P-gp). This was...
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