Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis.

Arthritis research & therapy - 1 Jan 2006

Nandakumar Kutty Selva, Holmdahl Rikard

Abstract excerpt

During the development of rheumatoid arthritis (RA) autoantibodies to IgG-Fc, citrullinated proteins, collagen type II (CII), glucose 6 phosphoisomerase (G6PI) and some other self-antigens appear. Of these, a pathogenic effect of the anti-CII and anti-G6PI antibodies is well demonstrated using animal models. These new antibody mediated arthritis models have proven to be very useful for studies involved in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies
Share to Antibody Specificity
Share to Arthritis, Experimental

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Autoantibodies

Share to Glucose-6-Phosphate Isomerase

Share to Mice, Inbred DBA

Share to Receptors, Antigen, T-Cell

Share to Rheumatoid Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 17254316
DOI: 10.1186/ar2089
PMCID: PMC1794524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis.PMID 17254316Read ↗

Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes.Semantic proximity Read ↗

The role of the complement and the Fc gamma R system in the pathogenesis of arthritis.Semantic proximity Read ↗

Animal Models in Rheumatoid Arthritis: Is There a Correlation Between Autoantibodies in Human Pathology and Animal Models?Semantic proximity Read ↗

Anti-Citrullinated Protein Antibodies in Patients with Rheumatoid Arthritis: Biological Effects and Mechanisms of ImmunopathogenesisSemantic proximity Read ↗

IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritisSemantic proximity Read ↗

Induction and Suppression of Collagen-Induced Arthritis Is Dependent on Distinct Fcγ ReceptorsSemantic proximity Read ↗

Recombinant Human IgG1-Hexamer Reduces Pathogenic Autoantibodies in the K/BxN Mouse Model of Arthritis Independent of FcRnSemantic proximity Read ↗

Antibodies to citrullinated proteins: molecular interactions and arthritogenicitySemantic proximity Read ↗

KRN/I-Ag7 mouse arthritis is independent of complement C3.Semantic proximity Read ↗

Anti–Citrullinated Protein Antibodies With Multiple Specificities Ameliorate Collagen Antibody–Induced Arthritis in a Time‐Dependent MannerSemantic proximity Read ↗

Common mechanisms in immune-mediated inflammatory disease.Semantic proximity Read ↗

Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.