Article
Large-scale analysis of antigenic diversity of T-cell epitopes in dengue virus
1 Dec 2006
Abstract excerpt
BACKGROUND: Antigenic diversity in dengue virus strains has been studied, but large-scale and detailed systematic analyses have not been reported. In this study, we report a bioinformatics method for analyzing viral antigenic diversity in the context of T-cell mediated immune responses. We applied this method to study the relationship between short-peptide antigenic diversity and protein sequence diversity of...
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