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Virulence, immunogenicity and vaccine properties of a novel chimeric pestivirus

25 Jan 2007

Abstract excerpt

A chimeric pestivirus of border disease virus Gifhorn and bovine viral diarrhea virus CP7 (Meyers et al., 1996) was constructed. Virulence, immunogenicity and vaccine properties of the chimeric virus were studied in a vaccination-challenge experiment in pigs. The chimeric virus proved to be avirulent and neither chimeric virus nor viral RNA was detected in serum after vaccination. The safety of the vaccine was...

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PMID: 17251566
DOI: 10.1099/vir.0.82453-0

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