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Article

Rapid Engineering of Foot-and-Mouth Disease Vaccine and Challenge Viruses

1 Jun 2017

Abstract excerpt

ABSTRACT There are seven antigenically distinct serotypes of foot-and-mouth disease virus (FMDV), each of which has intratypic variants. In the present study, we have developed methods to efficiently generate promising vaccines against seven serotypes or subtypes. The capsid-encoding gene (P1) of the vaccine strain O1/Manisa/Turkey/69 was replaced with the amplified or synthetic genes from the O, A, Asia1, C,...

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Identifiers

PMID: 28566375
DOI: 10.1128/jvi.00155-17

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