Article
GSTT2 promoter polymorphisms and colorectal cancer risk.
BMC cancer - 25 Jan 2007
Jang Sang-Geun, Kim Il-Jin, Kang Hio Chung, Park Hye-Won, Ahn Sun-A, Yoon Hyun-Ju, Kim Kun, Shin Hai-Rim, Lee Jin Soo, Park Jae-Gahb
Abstract excerpt
BACKGROUND: Glutathione S-transferases are a group of enzymes that participate in detoxification and defense mechanisms against toxic carcinogens and other compounds. These enzymes play an important role in human carcinogenesis. In the present study, we sought to determine whether GSTT2 promoter single nucleotide polymorphisms (SNPs) are associated with colorectal cancer risk. METHODS: A total of 436 colorectal...
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