Article
Classic thrombophilic gene variants.
Thrombosis and haemostasis - 1 Nov 2015
Mannucci Pier Mannuccio, Franchini Massimo
Abstract excerpt
Thrombophilia is defined as a condition predisposing to the development of venous thromboembolism (VTE) on the basis of a hypercoagulable state. Over the past decades, great advances in the pathogenesis of VTE have been made and nowadays it is well established that a thrombophilic state may be associated with acquired and/or inherited factors. The rare loss-of-function mutations of the genes encoding natural...
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